Oral Oncology
Volume 36, Issue 1 , Pages 37-41 , January 2000

Response of human oral epithelial cells to oxidative damage and the effect of vitamin E

  • G.A Royack

      Affiliations

    • Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Washington, Seattle, WA, USA
    • ,
  • M.P Nguyen

      Affiliations

    • Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Washington, Seattle, WA, USA
    • ,
  • D.C Tong

      Affiliations

    • Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Washington, Seattle, WA, USA
    • ,
  • M Poot

      Affiliations

    • Department of Pathology, School of Medicine, University of Washington, Seattle, WA, USA
    • ,
  • D Oda

      Affiliations

    • Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Washington, Seattle, WA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-206-616-4748; fax: +1-206-685-7222

Received 6 April 1999 ,Accepted 22 April 1999.

References 

  1. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 2nd Edition. Oxford: Clarendon; 1989;
  2. Weiss SJ. Tissue destruction by neutrophils. New England Journal of Medicine. 1989;320:365–367
  3. Wright DT, Cohn LA, Li H, Fischer B, Li CM, Adler KB. Interactions of oxygen radicals with airway epithelium. Environ Health Perspect. 1994;102(Suppl 10):85–90
  4. Diplock AT. Antioxidant nutrients and disease prevention: an overview. Am J Clin Nutr. 1991;53:189S–193S
  5. Chen LH, Boissonneault GA, Glauert HP. Vitamin C, vitamin E and cancer: a review of epidemiological and experimental data. Anticancer Research. 1988;8:739–748
  6. Trickler D, Shklar G. Prevention by vitamin E of experimental oral carcinogenesis. JNCI. 1987;78:165–169
  7. Odukoya O, Hawach F, Shklar G. Retardation of experimental oral cancer by topical vitamin E. Nutr. Cancer. 1984;6:98–104
  8. Weerapradist W, Shklar G. Vitamin E inhibition of hamster buccal pouch carcinogenesis: a gross, histologic and ultrastructural study. Oral Surg. 1982;54:304–312
  9. Shklar G. Oral mucosal carcinogenesis in hamsters: inhibition by vitamin E. JNCI. 1982;68:791–797
  10. Oda D, Watson E. Human oral epithelial cell culture I. Improved conditions for reproducible culture in serum-free medium. In Vitro. 1990;26:589–595
  11. Rabionvitch P. DNA content histogram and cell cycle analysis. Methods Cell Biology. 1994;41:263–296
  12. Zweier JL, Periannan K, Lutty GA. Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues. Proc Natl Acad Sci USA. 1988;85:4046–4050
  13. Oda D, Savard CE, Eng L, Sekijima J, Haigh G, Lee SP. Reconstituted human oral and esophageal mucosa in culture. In Vitro Cell Dev. Biol.—Animal. 1998;34:46–52
  14. Roots R, Okada S. Estimation of life times and diffusion differences of radicals involved in X-ray-induced DNA strand breaks or killing of mammalian cells. Radiat Res. 1975;64:306–320
  15. Schraufstätter I, Hyslop PA, Jackson JH, Cochrane CG. Oxidant-induced DNA damage of target cells. J Clin Invest. 1988;82:1040–1050
  16. Burton GW, Traber MG. Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annu Rev Nutr. 1990;10:357–382
  17. Gadbois DM, Lehnert BE. Cell cycle response to DNA damage differs in bronchial epithelial cells and lung fibroblasts. Cancer Res. 1997;57:3174–3179
  18. McKenzie SJ, Baker MS, Buffinton GD, Doe WF. Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease. J Clin Invest. 1996;98:136–141

PII: S1368-8375(99)00047-0

Oral Oncology
Volume 36, Issue 1 , Pages 37-41 , January 2000

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