Oral Oncology
Volume 46, Issue 8 , Pages 618-621 , August 2010

Nasopharyngeal mucoepidermoid carcinoma: A review of 13 cases

  • Xi-mei Zhang

      Affiliations

    • Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Jian-zhong Cao

      Affiliations

    • Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Jing-wei Luo

      Affiliations

    • Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
    • Corresponding Author InformationCorresponding author. Address: Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, People’s Republic of China. Tel.: +86 10 87788282; fax: +86 10 67706153.
  • ,
  • Guo-zhen Xu

      Affiliations

    • Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Li Gao

      Affiliations

    • Department of Radiation Oncology, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Shao-yan Liu

      Affiliations

    • Department of Head and Neck Surgery, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Zhen-gang Xu

      Affiliations

    • Department of Head and Neck Surgery, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China
  • ,
  • Ping-zhang Tang

      Affiliations

    • Department of Head and Neck Surgery, Cancer Hospital of Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People’s Republic of China

Received 26 March 2010 ,Revised 5 June 2010 ,Accepted 7 June 2010.

References 

  1. Stewart FW, Foote FW, Becker WF. Mucoepidermoid tumors of salivary glands. Ann Surg. 1945;122:820–844
  2. Cawson RA, Gleeson MJ, Eveson JW. The pathology and surgery of the salivary glands. Oxford: ISIS Medical Media; 1997;p. 117–69
  3. Ellis GL, Auclair PL. Atlas of tumor pathology, tumors of the salivary glands, series 3, fascicle 17. Washington, DC: Armed Forces Institute of Pathology; 1996;p. 155–75, 353–5
  4. Brandwein MS, Ivanov K, Wallace DI, Hille JJ, Wang B, Fahmy A, et al. Mucoepidermoid carcinoma – a clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol. 2001;25:835–845
  5. Schramm VL, Imola MJ. Management of nasopharyngeal salivary gland malignancy. Laryngoscope. 2001;111:1533–1544
  6. Kuo TT, Tsang NM. Salivary gland type nasopharyngeal carcinoma. A histologic, immunohistochemical, and Epstein-Barr Virus study of 15 cases including a psammomatous mucoepidermoid carcinoma. Am J Surg Pathol. 2001;25:80–86
  7. Rzaev RM. Mucoepidermoid carcinoma of the nasopharynx. Vestn Otorinolaringol. 1986;4:78–79
  8. Kusafuka K, Takizawa Y, Iida Y, Ebihara M, Onitsuka T, Kameya T. Primary nasopharyngeal mucoepidermoid carcinoma in Japanese patients: two case reports with histochemical and immunohistochemical analysis and a review of the literature. Virchows Arch. 2007;450:343–348
  9. Kim YH, Chae SW, Jung HH. Mucoepidermoid carcinoma arising from the eustachian tube and middle ear. J Laryngol Otol. 2003;117:202–204
  10. Spiro RH, Koss LG, Hajdu SI, Strong EW. Tumors of minor salivary origin: a clinicopathology study of 492 cases. Cancer. 1973;31:117–129
  11. Garden AS, Weber RS, Ang KK, Morrison WH, Matre J, Peters LJ. Postoperative radiation therapy for malignant tumors of minor salivary glands. Cancer. 1994;73:2563–2569
  12. Ellis ER, Million RR, Mendenhall WM, Parsons JT, Cassisi NJ. The use of radiation therapy in the management of minor salivary gland tumors. Int J Radiat Oncol Biol Phys. 1988;15:613–617
  13. Qiu F, Hua YJ, Guo L. Mucoepidermoid carcinoma of nasopharynx: a report of twelve cases. Chin J Cancer. 2005;24:362–364
  14. Thompson LD. Mucoepidermoid carcinoma. Ear Nose Throat J. 2005;84:762–763
  15. Guzzo M, Andreola S, Sirizzotti G, Cantu G. Mucoepidermoid carcinoma of the salivary glands: clinicopathologic review of 108 patients treated at the National Cancer Institute of Milan. Ann Surg Oncol. 2002;9:688–695
  16. Pires FR, Almeida OP, Araújo VC, Kowalski LP. Prognostic factors in head and neck mucoepidermoid carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130:174–180
  17. Kokemueller H, Brueggemann N, Swennen G, Eckardt A. Mucoepidermoid carcinoma of the salivary glands – clinical review of 42 cases. Oral Oncol. 2005;41:3–10
  18. Yi JL, Huang XD, Gao L, et al. Nasopharyngeal carcinoma treated by radical radiotherapy alone: ten-year experience of a single institution. Int J Radiat Oncol Biol Phys. 2006;65:161–168
  19. Ellis ER, Million RR, Mendenhall WM, Parsons JT, Cassisi NJ. The use of radiation therapy in the management of minor salivary gland tumors. Int J Radiat Oncol Biol Phys. 1988;15:613–617
  20. Wang CC. Malignant tumors of the salivary glands. In: Radiation therapy for head and neck neoplasms. Chicago: Year Book Medical Publishers, Inc.; 1990;
  21. Shonai T, Hareyama M, Sakata KI, Oouchi A, Nagakura H, Koito K, et al. Mucoepidermoid carcinoma of the larynx: a case which responded completely to radiotherapy and a review of the literature. Jpn J Clin Oncol. 1998;28:339–342
  22. Kawaida M, Fukuda H, Kohno N, Saito H, Ichikawa G, Ikari T. Mucoepidermoid tumor of the larynx: a case which responded completely to radiotherapy. Jibi to Rynsyo. 1993;39:429–434[in Japanese]
  23. Yoshimura T, Suenaga T, Ozaki H. A case of laryngeal mucoepidermoid carcinoma in subglottis. Jibi Inkoka Rynsyo. 1990;40(Suppl.):60;[in Japanese]
  24. Tran L, Jonas S, Sadeghi A. Salivary gland tumors of the oral cavity. Int J Radiat Oncol Biol Phys. 1990;18:413–417
  25. North CA, Lee DJ, Piantadosi S. Carcinoma of the major salivary glands treated by surgery or surgery plus postoperative radiotherapy. Int J Radiat Oncol Biol Phys. 1990;18:1319–1326
  26. Hosokawa Y, Shirato H, Kagei K, Hashimoto S, Nishioka T, Tei K, et al. Role of radiotherapy for mucoepidermoid carcinoma of salivary gland. Oral Oncol. 1999;35:105–111
  27. Anderson JN, Beenken SW, Crowe R, Soong SJ, Peters G, Maddox WA, et al. Prognostic factors in minor salivary gland cancer. Head Neck. 1995;17:480–486
  28. Nance MA, Seethala RR, Wang Y, Chiosea SI, Myers EN, Johnson JT, et al. Treatment and survival outcomes based on histological grading in patients with head and neck mucoepidermoid carcinoma. Cancer. 2008;113:2082–2089
  29. Goode RK, Auclair PL, Ellis GL. Mucoepidermoid carcinoma of the major salivary glands. Clinical and histopathologic analysis of 234 cases with evaluation of grading criteria. Cancer. 1998;82:1217–1224

PII: S1368-8375(10)00184-3

doi: 10.1016/j.oraloncology.2010.06.001

Oral Oncology
Volume 46, Issue 8 , Pages 618-621 , August 2010