Oral Oncology
Volume 46, Issue 5 , Pages 349-354 , May 2010

Impact of submandibular gland excision on salivary gland function in head and neck cancer patients

  • G.C. Jaguar

      Affiliations

    • Stomatology Department – Hospital A.C. Camargo, São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. Address: Departamento de Estomatologia – Hospital do Câncer AC Camargo, R: Prof. Antônio Prudente, 211, Bairro: Liberdade, São Paulo, SP CEP: 01509-900, Brazil. Tel.: +55 11 2189 5129; fax: +55 11 2189 5133.
    • ,
  • E.N.P. Lima

      Affiliations

    • Nuclear Medicine Department – Hospital A.C. Camargo, São Paulo, Brazil
    • ,
  • L.P. Kowalski

      Affiliations

    • Head and Neck Department – Hospital A.C. Camargo, São Paulo, Brazil
    • ,
  • A.C. Pellizon

      Affiliations

    • Radiotherapy Department – Hospital A.C. Camargo, São Paulo, Brazil
    • ,
  • A.L. Carvalho

      Affiliations

    • Head and Neck Department – Hospital do Câncer de Barretos, São Paulo, Brazil
    • ,
  • F.A. Alves

      Affiliations

    • Stomatology Department – Hospital A.C. Camargo, São Paulo, Brazil

Received 2 October 2009 ,Revised 9 November 2009 ,Accepted 10 November 2009.

References 

  1. Ferlito A, Robbins KT, Silver CE, Hasegawa Y, Rinaldo A. Classification of neck dissections: an evolving system. Auris Nasus Larynx. 2009;36(2):127–134
  2. Cunning DM, Lipke N, Wax MK. Significance of unilateral submandibular gland excision on salivary flow in noncancer patients. Laryngoscope. 1998;108(6):812–815
  3. Marunick MT, Mahmassani O, Klein B, Seyedsadr M. The effect of surgical intervention for head and neck cancer on whole salivary flow: a pilot study. J Prosthet Dent. 1993;70(2):154–157
  4. Jacob RF, Weber RS, King GE. Whole salivary flow rates following submandibular gland resection. Head Neck. 1996;18(3):242–247
  5. Valdés Olmos RA, Keus RB, Takes RP, van Tinteren H, Baris G, Hilgers FJ, et al. Scintigraphic assessment of salivary function and excretion response in radiation-induced injury of the major salivary glands. Cancer. 1994;12:2886–2893
  6. Münter MW, Karger CP, Hoffner SG, Hof H, Thilmann C, Rudat V, et al. Evaluation of salivary gland function after treatment of head-and-neck tumours with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy. Int J Radiat Oncol Biol Phys. 2004;1:175–178
  7. Navazesh M, Kumar SK. Measuring salivary flow: challenges and opportunities. J Am Dent Assoc. 2008;139(Suppl.):35S–40S
  8. Malpani BL, Samuel AM, Ray S. Quantification of salivary gland function in thyroid cancer patients treated with radioiodine. Int J Radiat Oncol Biol Phys. 1996;35(3):535–540
  9. Eisbruch A, Rhodus N, Rosenthal D, Murphy B, Rasch C, Sonis S, et al. How should we measure and report radiotherapy-induced xerostomia?. Semin Radiat Oncol. 2003;3:226–234
  10. Kowalski LP, Magrin J, Waksman G, Santo GF, Lopes ME, de Paula RP, et al. Supraomohyoid neck dissection in the treatment of head and neck tumours. Survival results in 212 cases. Arch Otolaryngol Head Neck Surg. 1993;119(9):958–963
  11. Robbins KT, Medina JE, Wolfe GT, Levine PA, Sessions RB, Pruet CW. Standardizing neck dissection terminology. Official report of the academy’s committee for head and neck surgery and oncology. Arch Otolaryngol Head Neck Surg. 1991;117(6):601–605
  12. Ferlito A, Rinaldo A, Robbins KT, Silver CE. Neck dissection: past, present and future?. J Laryngol Otol. 2006;120(2):87–92
  13. Robbins KT, Clayman G, Levine PA, Medina J, Sessions R, Shaha A, et al. American head and neck society; American academy of otolaryngology – head and neck surgery. Neck dissection classification update: revisions proposed by the American head and neck society and the American academy of otolaryngology – head and neck surgery. Arch Otolaryngol Head Neck Surg. 2002;128(7):751–758
  14. Humphrey SP, Williamson RT. A review of saliva: normal composition, flow, and function. J Prosthet Dent. 2001;2:162–169
  15. Pedersen AM, Bardow A, Jensen SB, Nauntofte B. Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Dis. 2002;3:117–129
  16. Porter SR, Scully C, Hegarty AM. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97(1):28–46
  17. Pow EH, McMillan AS, Leung WK, Wong MC, Kwong DL. Salivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma. Clin Oral Investig. 2003;4:230–234
  18. Jensen SB, Pedersen AM, Reibel J, Nauntofte B. Xerostomia and hypofunction of the salivary glands in cancer therapy. Support Care Cancer. 2003;11:207–225
  19. Klutmann S, Bohuslavizki KH, Kröger S, et al. Quantitative salivary gland scintigraphy. J Nucl Med Technol. 1999;27:20–26
  20. Loutfi I, Nair MK, Ebrahim AK. Salivary gland scintigraphy: the use of semiquantitative analysis for uptake and clearance. J Nucl Med Technol. 2003;31:81–85

PII: S1368-8375(10)00051-5

doi: 10.1016/j.oraloncology.2009.11.018

Oral Oncology
Volume 46, Issue 5 , Pages 349-354 , May 2010

Article Tools

* Image Usage & Resolution