Oral Oncology
Volume 46, Issue 4 , Pages 263-270 , April 2010

Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B

  • Guangying Qi

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Yasusei Kudo

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
    • Corresponding Author InformationCorrespondence authors. Tel.: +81 82 257 5634; fax: +81 82 257 5619 (Y. Kudo).
  • ,
  • Toshinori Ando

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Takaaki Tsunematsu

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Natsumi Shimizu

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Samadarani B.S.M. Siriwardena

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Maki Yoshida

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Mohammad Reza Keikhaee

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
  • ,
  • Ikuko Ogawa

      Affiliations

    • Center of Oral Clinical Examination, Hiroshima University Hospital, Hiroshima 734-8553, Japan
  • ,
  • Takashi Takata

      Affiliations

    • Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
    • Corresponding Author InformationCorrespondence authors. Tel.: +81 82 257 5634; fax: +81 82 257 5619 (Y. Kudo).

Received 8 December 2009 ,Revised 23 December 2009 ,Accepted 4 January 2010.

References 

  1. Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL. Cloning and expression of apoptosis inhibition protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc Natl Acad Sci USA. 1996;93(10):4974–4978
  2. Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, Survivin, expressed in cancer and lymphoma. Nat Med. 1997;3(8):917–921
  3. Chiou SK, Jones MK, Tarnawski AS. Survivin an anti-apoptosis protein: its biological roles and implications for cancer and beyond. Med Sci Monit. 2003;9(4):125–129
  4. Tanaka K, Iwamoto S, Gon G, Nohara T, Iwamoto M, Tanigawa N. Expression of Survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res. 2000;6(1):127–134
  5. Adida C, Haioun C, Gaulard P, Lepage E, Morel P, Briere J, et al. Prognostic significance of Survivin expression in diffuse large B-cell lymphomas. Blood. 2000;96(5):1921–1925
  6. Wakana Y, Kasuya K, Katayanagi S, et al. Oncol Rep. 2002;9(6):1213–1218
  7. Kawasaki H, Altieri DC, Lu CD, Toyoda M, Tenjo T, Tanigawa N. Inhibition of apoptosis by Survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 1998;58(22):5071–5074
  8. Sui L, Dong Y, Ohno M, Watanabe Y, Sugimoto K, Tokuda M. Survivin expression and its correlation with cell proliferation and prognosis in epithelial ovarian tumours. Int J Oncol. 2002;21(2):315–320
  9. Artieri DC. The case for Survivin as a regulator of microtubule dynamics and cell-death decisions. Curr Opin Cell Biol. 2006;18(6):609–615
  10. Gassmann R, Carvalho A, Henzing AJ, Ruchaud S, Hudson DF, Honda R, et al. Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol. 2004;166(2):179–191
  11. Lens SM, Vader G, Medema RH. The case for Survivin as mitotic regulator. Curr Opin Cell Biol. 2006;18(6):616–622
  12. Bolton MA, Lan W, Powers SE, McCleland ML, Kuang J, Stukenberg PT. Aurora B kinase exists in a complex with Survivin and INCENP and its kinase activity is stimulated by Survivin binding and phosphorylation. Mol Biol Cell. 2002;13(9):3064–3077
  13. Honda R, Korner R, Nigg EA. Exploring the functional interactions between Aurora B, INCENP, and Survivin in mitosis. Mol Biol Cell. 2003;14(8):3325–3341
  14. Adams RR, Eckley DM, Vagnarelli P, Wheatley SP, Gerloff DL, Mackay AM, et al. Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. Chromosome. 2001;110(2):65–74
  15. Beardmore VA, Ahonen LJ, Gorbsky GJ, Kallio MJ. Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity. J Cell Sci. 2004;117(18):4033–4042
  16. Qi G, Ogawa I, Kudo Y, Miyauchi M, Siriwardena BS, Shimamoto F, et al. Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer. Virchows Arch. 2007;450(3):297–302
  17. Stauber RH, Mann W, Knauer SK. Nuclear and cytoplasmic Survivin: molecular mechanism, prognostic, and therapeutic potential. Cancer Res. 2007;67(13):5999–6002
  18. Lin CY, Hung HC, Kuo RC, Chiang CP, Kuo MY. Survivin expression predicts poorer prognosis in patients with areca quid chewing-related oral squamous cell carcinoma in Taiwan. Oral Oncol. 2005;41(6):645–654
  19. Jane C, Nerurkar AV, Shirsat NV, Deshpande RB, Amrapurkar AD, Karjodkar FR. Increased Survivin expression in high-grade oral squamous cell carcinoma: a study in Indian tobacco chewers. J Oral Pathol Med. 2006;35(10):595–601
  20. Li F, Yang J, Ramnath N, Javle MM, Tan D. Nuclear or cytoplasmic expression of Survivin: what is the significance?. Int J Cancer. 2005;114(4):509–512
  21. Engels K, Knauer S, Metzler D, Simf C, Struschka O, Bier C, et al. Dynamic intracellular Survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early rognostic marker. J Pathol. 2007;211(5):532–540
  22. Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411(6836):494–498
  23. Knauer SK, Bier C, Habtemichael N, Stauber RH. The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function. EMBO Rep. 2006;7(12):1259–1265
  24. Colnaghi R, Connell CM, Barrett RM, Wheatley SP. Separating the anti-apoptotic and mitotic roles of Survivin. J Biol Chem. 2006;281(44):33450–33456
  25. Marioni G, Bedogni A, Giacomelli L, Ferraro SM, Bertolin A, Facco E, et al. Survivin expression is significantly higher in pN+ oral and oropharyngeal primary squamous cell carcinomas than in pN0 carcinomas. Acta Otolaryngol. 2005;125(11):1218–1223
  26. Grabowski P, Kuhnel T, Muhr-Wilkenshoff F, Heine B, Stein H, Höpfner M, et al. Prognostic value of nuclear Survivin expression in oesophageal squamous cell carcinoma. Br J cancer. 2003;88(1):115–119
  27. Okada E, Murai Y, Matsui K, Isizawa S, Cheng C, Masuda M, et al. Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients. Cancer Lett. 2001;163(1):109–116
  28. Tonini G, Vincenzi B, Santini D, Scarpa S, Vasaturo T, Malacrino C, et al. Nuclear and cytoplasmic expression of Survivin in 67 surgically resected pancreatic cancer patients. Br J cancer. 2005;92(12):2225–2232
  29. Tatsuka M, Katayama H, Ota T, Tanaka T, Odashima S, Suzuki F, et al. Multinuclearity and increased ploidy caused by overexpression of the Aurora B and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res. 1998;58(21):4811–4816
  30. Kanda A, Kawai H, Suto S, Kitajima S, Sato S, Takata T, et al. Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation. Oncogene. 2006;24(49):7266–7272
  31. Temme A, Rieber EP, Schmitz M, Morgenroth A, Weigle B, Rieger MA, et al. Increased p21(ras) activity in human fibroblasts transduced with Survivin enhances cell proliferation. Biochem Biophys Res Commun. 2005;327(3):765–773

PII: S1368-8375(10)00005-9

doi: 10.1016/j.oraloncology.2010.01.004

Oral Oncology
Volume 46, Issue 4 , Pages 263-270 , April 2010