Oral Oncology
Volume 46, Issue 4 , Pages 255-262, April 2010

Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis

  • Yu-Chu Wang

      Affiliations

    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • These authors contributed equally to this work.
    • ,
  • Yi-Shan Tsai

      Affiliations

    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • These authors contributed equally to this work.
    • ,
  • Jau-Ling Huang

      Affiliations

    • Department of Bioscience Technology, College of Health Science, Chang Jung Christian University, Tainan, Taiwan
    • ,
  • Ka-Wo Lee

      Affiliations

    • Department of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Ching-Chuan Kuo

      Affiliations

    • National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    • ,
  • Chung-Sheng Wang

      Affiliations

    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • A-Mei Huang

      Affiliations

    • Department of Biochemistry, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Jang-Yang Chang

      Affiliations

    • National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan
    • ,
  • Yuh-Jyh Jong

      Affiliations

    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Department of Pediatrics and Laboratory Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    • ,
  • Chang-Shen Lin

      Affiliations

    • Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Address: Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shi-Chuan 1st Rd., Kaohsiung 807, Taiwan. Tel.: +886 7 3121101 2019; fax: +886 7 3218309.

Received 6 December 2009; received in revised form 28 December 2009; accepted 4 January 2010. published online 08 February 2010.

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PII: S1368-8375(10)00004-7

doi:10.1016/j.oraloncology.2010.01.003

Oral Oncology
Volume 46, Issue 4 , Pages 255-262, April 2010

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