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Oral Oncology
Volume 46, Issue 3
, Pages 172-177
, March 2010
Tapered dose versus constant drug exposure to anti-EGFR drugs on head-and-neck cancer xenografts. A comparison between cetuximab and gefitinib
References
- Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. Clin Cancer Res. 2001;7:4156–4163
- . Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839. Semin Oncol. 2001;28:56–66
- . Clinical advancement of EGFR inhibitors in cancer therapy. Methods Mol Biol. 2006;327:189–202
- Cetuximab for treatment of metastatic colorectal cancer. Ann Oncol. 2006;17:vii66–vii67
- . Targeting the epidermal growth factor receptor. Trials in head and neck and lung cancer. Oncology (Williston Park). 2006;20:153–161
- . EGFR antagonists in cancer treatment. N Engl J Med. 2008;358:1160–1174
- . EGFR targeting therapies: monoclonal antibodies versus tyrosine kinase inhibitors. Similarities and differences. Crit Rev Oncol Hematol. 2007;62:53–61
- Radiotherapy plus cetuximab for squamous cell carcinoma of the head and neck. N Eng J Med. 2006;354:567–578
- Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Eng J Med. 2008;359:1116–1127
- . Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor. Cancer Res. 2004;64:5355–5362
- Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J Clin Oncol. 1993;11:1873–1878
- . Biology of interactions: antiepidermal growth factor receptor agents. J Clin Oncol. 2007;25:4057–4065
- Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol. 2007;25:2171–2177
- Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol. 2003;21:1980–1987
- . Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol. 2006;24:2666–2672
- . EGFR-targeting drugs in combination with cytotoxic agents: from bench to bedside, a contrasted reality. Br J Cancer. 2008;99:1–5
- . Targeted therapy in head and neck cancer. Cancer. 2008;112:2635–2645
- Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex. J Biol Chem. 2001;276:27677–27684
- Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents. Cancer Res. 2005;65:3003–3010
- . Gene expression patterns and profile changes pre- and post-erlotinib treatment in patients with metastatic breast cancer. Clin Cancer Res. 2005;11:6226–6232
- Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. EMBO J. 2002;21:2407–2417
- Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Eng J Med. 2008;359:1116–1127
☆ Results presented in part during the 2008 annual meeting of the American Association for Cancer Research (AACR).
PII: S1368-8375(09)00979-8
doi: 10.1016/j.oraloncology.2009.11.010
© 2009 Elsevier Ltd. All rights reserved.
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Oral Oncology
Volume 46, Issue 3
, Pages 172-177
, March 2010
