Oral Oncology
Volume 45, Issue 12 , Pages e232-e238 , December 2009

Oncocytoma of the salivary glands: A clinicopathologic and immunohistochemical study

  • Chuan-Xiang Zhou

      Affiliations

    • Corresponding Author InformationCorresponding author. Address: Department of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing 100081, PR China. Tel.: +86 10 62179977; fax: +86 10 62173402.
    • ,
  • Yan Gao

Received 15 July 2009 ,Revised 19 August 2009 ,Accepted 19 August 2009.

References 

  1. Huvos AG. Oncocytoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumours: pathology and genetics, head and neck tumours. Lyon: IARC Press; 2005. p. 242–3.
  2. Brandwein MS, Huvos AG. Oncocytic tumors of major salivary glands: a study of 68 cases with follow-up of 44 patients. Am J Surg Pathol. 1991;15(6):514–528
  3. Capone RB, Ha PK, Westra WH, Pilkington TM, Sciubba JJ, Koch WM, et al. Oncocytic neoplasms of the parotid gland: a 16-year institutional review. Otolaryngol Head Neck Surg. 2002;126(6):657–662
  4. Thompson LD, Wenig BM, Ellis GL. Oncocytomas of the submandibular gland. A series of 22 cases and a review of the literature. Cancer. 1996;78(11):2281–2287
  5. Palmer TJ, Gleeson MJ, Eveson JW, Cawson RA. Oncocytic adenomas and oncocytic hyperplasia of salivary glands: a clinicopathological study of 26 cases. Histopathology. 1990;16(5):487–493
  6. Dardick I, Birek C, Lingen MW, Rowe PE. Differentiation and the cytomorphology of salivary gland tumors with specific reference to oncocytic metaplasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88(6):691–701
  7. Young JA. Diagnostic problems in fine needle aspiration cytoplathology of salivary glands. J Clin Pathol. 1994;47(3):193–198
  8. Skalowa A, Michal M, Ryska A, Simpson RH, Kinkor Z, Walter J, et al. Oncocytic myoepithelioma and pleomorphic adenoma of the salivary glands. Virchows Arch. 1999;434(6):537–546
  9. Verma K, Kapila K. Salivary gland tumors with a prominent oncocytic component. Cytologic findings and differential diagnosis of oncocytomas and Warthin’s tumor on fine needle aspirates. Acta Cytol. 2003;47(2):221–226
  10. Ito K, Tsukuda M, Kawabe R, Nakagawa C, Matsushita K, Kubota A, et al. Benign and malignant oncocytoma of the salivary glands with an immunohistochemical evaluation of Ki-67. ORL J Otorhinolaryngol Relat Spec. 2000;62(6):338–341
  11. Zajicek G. The histogenesis of glandular neoplasia. Med Hypotheses. 1981;7(10):1241–1251
  12. Leonardo E, Volante M, Barbareschi M, Cavazza A, Paolo Dei Tos A, Bussolati G, et al. Cell membrane reactivity of MIB-1 antibody to Ki67 in human tumors: fact or artifact?. Appl Immunohistochem Mol Morphol. 2007;15(2):220–223
  13. Hirokawa M, Shimizu M, Manabe T, Kuroda M, Mizoguchi Y. Hyalinizing trabecular adenoma of the thyroid: its unusual cytoplasmic immunopositivity for MIB1. Pathol Int. 1995;45(5):399–401
  14. Hattori H. Sclerosing hemangioma of the lung is positive for MIB-1 in cell membrane and cytoplasmic staining pattern. Histopathology. 2002;40(3):291–293
  15. Ellis GL. “Clear cell” oncocytoma of salivary gland. Hum Pathol. 1988;19(7):862–867
  16. Davy CL, Dardick I, Hammond E, Thomas MJ. Relationship of clear cell oncocytoma to mitochondrial-rich (typical) oncocytomas of parotid salivary gland. An ultrastructural study. Oral Surg Oral Med Oral Pathol. 1994;77(5):469–479
  17. Saqi A, Giorgadze TA, Eleazar J, Remotti F, Vaguez MF. Clear cell and eosinophilic oncocytomas of salivary gland: cytological variants or parallels?. Diagn Cytopathol. 2007;35(3):158–163

PII: S1368-8375(09)00889-6

doi: 10.1016/j.oraloncology.2009.08.004

Oral Oncology
Volume 45, Issue 12 , Pages e232-e238 , December 2009

Article Tools

* Image Usage & Resolution