Oral Oncology
Volume 45, Issue 12 , Pages 1011-1014, December 2009

Review of the molecular pathogenesis of the odontogenic keratocyst

Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

Received 13 July 2009; received in revised form 1 August 2009; accepted 17 August 2009. published online 05 October 2009.

Summary 

The odontogenic keratocyst (keratocystic odontogenic tumour) (OKC) is one of the most prevalent odontogenic tumours. Since its initial description, a number of studies have focused on different aspects of this lesion, attempting to explain its distinctive biological behaviour. In this review the authors address the main genetic and epigenetic alterations reported on this tumour. Although most of the knowledge on this field is not being used in the clinical practice, some perspectives of translational studies are discussed.

Keywords: Odontogenic keratocyst, Keratocystic odontogenic tumour, PTCH, Genetics, Epigenetics, Review

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1368-8375(09)00884-7

doi:10.1016/j.oraloncology.2009.08.003

Oral Oncology
Volume 45, Issue 12 , Pages 1011-1014, December 2009

Article Tools

* Image Usage & Resolution