Oral Oncology
Volume 40, Issue 8 , Pages 856-858, September 2004

Keratosis follicularis of the oral mucosa with oral squamous cell carcinoma

  • Marco Dolci

      Affiliations

    • Maxillofacial Surgery Section, University of Chieti, Italy
    • Dental and Maxillofacial Surgery Unit, S. Liberatore Hospital, Atri, Italy
    • ,
  • Gianfranco Favia

      Affiliations

    • Department of Dentistry, University of Bari, Italy
    • ,
  • Crispian Scully

      Affiliations

    • Eastman Dental Institute for Oral Health Care Sciences, University of London, UK
    • ,
  • Luca Di Alberti

      Affiliations

    • Maxillofacial Surgery Section, University of Chieti, Italy
    • Dental and Maxillofacial Surgery Unit, S. Liberatore Hospital, Atri, Italy
    • Corresponding Author InformationCorresponding author. Via Colonnetta, 22-A, 66013 Chieti, Italy. Tel./fax: +39-871-562 938

Received 7 January 2004; accepted 12 January 2004.

Abstract 

Darier's disease or keratosis follicularis is a genodermatosis which may involve the oral mucosa. Malignant degeneration is rare. We report the first case of the combined manifestation of oral keratosis follicularis and oral squamous cell carcinoma and discuss the possible involvement of ATP2A2 (located in 12q23-24.1) which encodes the sarco/endoplasmic reticulum Ca2+-ATP isoform 2 (SERCA2), in the pathogenesis.

Keywords:  OSCC, Keratosis follicularis, Dermatosis

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1368-8375(04)00026-0

doi:10.1016/j.oraloncology.2004.01.016

Oral Oncology
Volume 40, Issue 8 , Pages 856-858, September 2004

Article Tools