Oral Oncology
Volume 40, Issue 7 , Pages 673-678 , August 2004

Detection of cervical intranodal metastasis in oral cancer using elastic scattering spectroscopy

  • W Jerjes

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University College London Hospitals, London WC1E 6AU, UK
  • ,
  • B Swinson

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University College London Hospitals, London WC1E 6AU, UK
  • ,
  • D Pickard

      Affiliations

    • National Medical Laser Centre, University College London, London W1W 7EJ, UK
  • ,
  • G.J Thomas

      Affiliations

    • Department of Oral Pathology, University College London Hospitals and Eastman Dental Institute, London WC1E 6JJ, UK
  • ,
  • C Hopper

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University College London Hospitals, London WC1E 6AU, UK
    • National Medical Laser Centre, University College London, London W1W 7EJ, UK
    • Department of Oral and Maxillofacial Surgery, The Eastman Dental Institute for Oral Health Care Sciences, London WC1X 8LD, UK
    • Corresponding Author InformationCorresponding author. Present address: Maxillofacial Unit, Mortimer Market, London WC1E 6AU, UK. Tel.: +44-207-380-9855

Received 25 November 2003 ,Accepted 22 December 2003.

References 

  1. Bigio IJ, Mourant JR. Ultraviolet an d visible spectroscopies for tissue diagnosis. Phys. Med. Biol. 1997;42:803–814
  2. Kessel D. Tumour localization and photosensitization by derivatives of hematoporphyrin: a review. IEEE J. Quantum Electron. 1987;23:1718
  3. Scott MA, Hopper C, Sahota A, et al.  Fluorescence photodiagnostics and photobleaching studies of cancerous lesions using ration imaging and spectroscopic techniques. Lasers Med. Sci. 2000;15:63–72
  4. Wang X, Krebs LJ, Al-Nuri M, et al.  A chemically labelled cytotoxic agent: two photon fluorophore for optical tracking of cellular pathway in chemotherapy. Proc. Natl. Acad. Sci. USA. 1999;96:11081–11084
  5. Redd DCB, Feng ZC, Yue KT, Gansler TS. Raman spectroscopic characterization of human breast tissues: implications for breast cancer diagnosis. Appl. Spectrosc. 1993;787–791
  6. Liu CH, Das BB, Sha Glassman WL, Tang GC, Yoo KM, Zhu HR, et al.  Raman, fluorescence and time––resolved light scattering as optical diagnostic techniques to separate diseased and normal biomedical media. J. Photochem. Photobiol. B: Biol. 1992;16:187–209
  7. Mourant JR, Bigio IJ, Boyer J, Johnson T, Lacey J, Bohorfoush AG, et al.  Elastic scattering spectroscopy as a diagnostic tool for differentiating pathologies in Gl tract. J. Biomed. Opt. 1996;1:192–199
  8. Bohorfoush AG. Tissue spectroscopy for gastrointestinal diseases. Endoscopy. 1996;28:372–380
  9. Perelman LT, Backman V, Wallace M, Zonios G, Manoharan R, Nusrat A, et al.  Observation of periodic fine structure in reflectance from biological tissue: a new technique for measuring nuclear size distribution. Phy. Rev. Lett. 1998;80:627–630
  10. Mourant JR, Heilscher AH, Eick AA, Johnson TM, Freyer JP. Evidence of intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells. Cancer (NY). 1998;53:366–374
  11. Naber SP. Molecular pathology: detection of neoplasia. N. Engl. J. Med. 1994;331:1508–1510
  12. Jen J, Powell SM, Papadopoulos N, et al.  Molecular determinants of dysplasia in colorectal lesions. Cancer Res. 1994;54:5523–5526
  13. Spechler SJ. Endoscopis assessment of premalignant oesophageal disorders. Gastrointest Endosc Clin N Am 1992;2:383–94
  14. Lashner BA. Colorectal cancer in ulcerative colitis patients: survival curves and surveillance. Clev. Clin. J. Med. 1994;61:272–275
  15. Melville DM, Jass JR, Morson BC, et al.  Observer study of the grading of dysplasia in ulcerative colitis: comparison with clinical outcome. Hum. Pathol. 1989;20:1008–1014
  16. Mourant JR, Boyer J, Hielscher A, Bigio IJ. Influence of scattering phase function on light transport measurements in turbid media performed with small source detector separations. Opt. Lett. 1996;21:546–548
  17. Bigio IJ, Bown SG, Briggs G, Kelley C, Lakhani S, Pickard D, et al.  Diagnosis of breast cancer using elastic scattering spectroscopy: preliminary clinical results. J. Biomed. Opt. 2000;5(2):221–228
  18. Woolgar JA, Vaughan ED, Scott J, Brown JS. Pathological findings in clinically false-negative and false-positive neck dissections for oral carcinoma. Ann. R. Coll. Surg. Engl. 1994;76:237–244
  19. Wide JM, White DW, Woolgar JA, Brown JS, Vaughan ED, Lewis-Jones HG. Magnetic resonance imaging in the assessment of cervical nodal metastasis in oral squamous cell carcinoma. Clin. Radiol. 1999;54(2):90–94
  20. Woolgar JA, Beirne JC, Vaughan ED, Lewis-Jones HG, Scott J, Brown JS. Correlation of histopathologic findings with clinical and radiologic assessments of cervical lymph node metastases in oral cancer. Int. J. Oral Maxillofac. Surg. 1995;24:30–37
  21. Haringsma J. Barrett's oesophagus: new diagnostic and therapeutic techniques. Scand. J. Gastroenterol. Suppl. 2002;(236):9–14
  22. Rollins AM, Sivak MV. Potential new endoscopic techniques for the earlier diagnosis of premalignancy. Best Pract. Res. Clin. Gastroenterol. 2001;15(2):227–247
  23. Mourant JR, Bigio I, Boyer J, Conn R, Johnson T, Shimada T. Spectroscopic diagnosis of bladder cancer with elastic light scattering. Lasers Surg. Med. 1995;17:350–357

PII: S1368-8375(04)00005-3

doi: 10.1016/j.oraloncology.2004.01.009

Oral Oncology
Volume 40, Issue 7 , Pages 673-678 , August 2004