Oral Oncology
Volume 40, Issue 5 , Pages 532-537 , May 2004

Expression of EGFR and Cerb-B2 as prognostic factors in cancer of the tongue

Received 13 August 2003 ,Accepted 10 November 2003.

References 

  1. Newman AN, Rice DH, Ossoff RH, et al.  Carcinoma of tongue in persons younger than thirty years of age. Arch. Otolayngol. 1983;109(5):302–304
  2. Son Y, Kapp D. Oral cavity and oropharyngeal cancer in a younger population. Cancer. 1985;55:441–444
  3. O’Sullivan GC, Collins JK, Kelly J, et al.  Micrometastasis: marker of metastatic potential or evidence of residual disease?. Gut. 1997;40(4):512–515
  4. Carpenter G, Cohen S. Epidermal growth factor. Ann. Rev. Biochem. 1988;57:443–478
  5. Tandon AK, Clark GM, Chamness GC, et al.  HER-2/neu oncogene protein and prognosis in breast cancer. J. Clin. Oncol. 1989;7:1120–1128
  6. Olapade-Olaopa EO, Moscatello DK, MacKay EH, et al.  Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer. Br. J. Cancer. 2000;82:186–194
  7. Garcia I, Visozo F, Andicoechea A, et al.  Clinical significance of epidermal growth factor receptor content in gastric cancer. Int. J. Biol. Markers. 2001;16(3):183–188
  8. Porebska I, Harlozinska A, Bojarowski T. Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomas. Tumor. Biol. 2000;21(2):105–115
  9. Baekelandt M, Kristensen GB, Trope CJ, et al.  Epidermal growth factor receptor expression has no independent prognostic significance in advanced ovarian cancer. Anticancer Res. 1999;19(5C):4469–4474
  10. Aziz SA, Pervez S, Khan S, et al.  Epidermal growth factor receptor (EGFR) as a prognostic marker: an immunohistochemical study on 315 consecutive breast carcinoma patients. J. Pak. Med. Assoc. 2000;52(3):104–110
  11. Grandis JR, Melhem MF, Gooding WE, et al.  Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J. Natl. Cancer. Inst. 1998;90(11):824–832
  12. Weinstein S, Nuamah I, Tucker J, et al.  Evaluation of HER-2/neu (c-erb B-2) oncogene expression in whole organ sections of supraglottic squamous cell carcinoma. Ann. Otol. Rhinol. Laryngol. 1996;105:275–279
  13. Beckhardt RN, Kiyokawa N, Xi L, et al.  HER-2/neu oncogene characterization in head and neck squamous cell carcinoma. Arch. Otolaryngol. Head Neck Surg. 1995;121:1265–1270
  14. Craven JM, Pavelic AP, Stambrook PJ, et al.  Expression of c-erb B-2 gene in human head and neck carcinoma. Anticancer Res. 1992;12:2273–2276
  15. Santini J, Formento JL, Francoual M, et al.  Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas. Head Neck. 1991;13(2):132–139
  16. Grandis JR, Melhem MF, Barnes EL, et al.  Quantitive immunohistochemical analysis of transformation growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma in head and neck. Cancer. 1996;78(6):1284–1292
  17. Hou L, Shi D, Tu SM, et al.  Oral cancer progression and c-erb B-2/neu proto-oncogene expression. Cancer Lett. 1992;65:215–220
  18. Katoh K, Nakanishi Y, Akimoto S, et al.  Correlation between Laminin-5 gamma2 chain expression and epidermal growth factor receptor expression and its clinicopathological significance in squamous cell carcinoma of the tongue. Oncology. 2002;62(4):318–326
  19. Shiga H, Rasmussen AA, Johnston PG, et al.  Prognostic value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent head and neck cancer. Head Neck. 2000;22(6):599–608
  20. Leonard JH, Kearsley JH, Chenevix-Trench G, et al.  Analysis of gene amplification in head-and-neck squamous-cell carcinoma. Int. J. Cancer. 1991;48(4):511–515
  21. Yamada T, Takagi M, Shioda S. Evaluation of epidermal growth factor receptor in squamous cell carcinoma of the oral cavity. Oral. Surg. Oral. Med. Oral. Pathol. 1992;73(1):67–70
  22. Kurokowa H, Yamashita Y, Takeda Z, et al.  Risk factors for late cervical lymph node metastasis in patients with stage 1 or 2 carcinoma of the tongue. Head Neck. 2002;24(8):731–736
  23. Maurizi M, Almador IG, Ferrandina G, et al.  Prognostic significance of epidermal growth factor in laryngeal squamous cell carcinoma. Br. J. Cancer. 1996;74:1253–1257
  24. Kazkasyasi M, Hucumenoglu S, Sirner GI, et al.  Over-expression of p53 and c-erb B-2 oncoproteins in laryngeal carcinoma. Eur. Arch. Otorhinolaryngol. 2001;258:329–335
  25. De Potter CR, Quatacker J, Aertens G, et al.  The subcellular localization of the neu protein in human normal and neoplastic cells. Int. J. Cancer. 1999;44:969–974
  26. Xia W, Lau YK, Zhang HZ, et al.  Combination of EGFR, HER-2/neu, and HER3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin. Cancer Res. 1999;5:4175–4181

PII: S1368-8375(03)00235-5

doi: 10.1016/j.oraloncology.2003.11.004

Oral Oncology
Volume 40, Issue 5 , Pages 532-537 , May 2004