Oral Oncology
Volume 40, Issue 1 , Pages 103-106, January 2004

Primary B-cell lymphoma of the tongue in a patient with systemic sclerosis

Division of Rheumatology, Thomas Jefferson University, 613 Curtis Bldg, 1015 Walnut Street, Philadelphia, PA 19107, USA

Received 12 June 2003; accepted 13 June 2003.

Abstract 

We report a patient with systemic sclerosis who had the unusual development of a large-cell B-cell lymphoma of the base of his tongue. Patients with systemic sclerosis display an increased incidence of malignant neoplasms, particularly, breast and lung carcinomas [Arthritis. Rheum. 36 (1993) 460; Ann. Rheum. Dis. 52 (1993) 531]. The description of this case adds further evidence to the possible interrelationship of systemic sclerosis and the development of malignant neoplasms. A careful review of the English medical literature disclosed that B-cell lymphoma of the tongue in a patient with systemic sclerosis is an association which has not been described previously.

Keywords:  Systemic sclerosis, Non-Hodgkin's lymphoma, Large cell lymphoma, B-cell lymphoma, Tongue lymphoma

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PII: S1368-8375(03)00137-4

doi:10.1016/S1368-8375(03)00137-4

Oral Oncology
Volume 40, Issue 1 , Pages 103-106, January 2004

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