Oral Oncology
Volume 38, Issue 4 , Pages 323-331 , June 2002

The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm?Part 2. Proliferation and genetic studies

  • Mervyn Shear

      Affiliations

    • Corresponding Author InformationTel.: +27-21-786-1172; fax +27-21-786-3447

Received 11 June 2001 ,Accepted 18 June 2001.

References 

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  2. Ogden GR, Chisholm DM, Kiddie RA, Lane DP. p53 protein in odontogenic cysts (Increased expression in some odontogenic keratocysts). J Clin Pathol. 1992;45:1007–1010
  3. Li T, Browne RM, Matthews JB. Quantification of PCNA+ cells within odontogenic jaw cyst epithelium. J Oral Pathol Med. 1994;23:184–189
  4. Li T, Browne RM, Matthews JB. Epithelial cell proliferation in odontogenic keratocysts (immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions). J Oral Pathol Med. 1995;24:221–226
  5. El Murtadi A, Grehan D, Toner M, McCartan BE. Proliferating cell nuclear antigen staining in syndrome and nonsyndrome odontogenic keratocysts. Oral Surg, Oral Med, Oral Pathol, Oral Radiol, Endod. 1996;81:217–220
  6. Piatelli A, Fioroni M, Santinelli A, Rubini C. Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts. Oral Oncology. 1998;34:408–412
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  15. Lench NJ, High AS, Markham AF, et al.  Investigation of chromosome 9q22.3-q31 DNA marker loss in odontogenic keratocysts. Oral Oncol, Eur J Cancer. 1996;32B:202–206
  16. Knudson AG. Mutation and cancer (statistical study of retinoblastoma). Proc Natl Acad Sci USA. 1971;68:823–830
  17. Lench NJ, Telford EAR, High AS, Markham AF, Wicking C, Wainwright BJ. Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome. Hum Genet. 1997;100:497–502
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  19. Barreto DC, Gomez RS, Bale AE, Boson WL, De Marco L. PTCH gene mutations in odontogenic keratocysts. J Dent Res. 2000;79:1418–1422
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  22. Levanat S, Pavelić B, Crnić I, Orešković S, Manojlović S. Involvement of PTCH gene in various noninflammatory cysts. J Mol Med. 2000;78:140–146

PII: S1368-8375(01)00066-5

Oral Oncology
Volume 38, Issue 4 , Pages 323-331 , June 2002

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