Oral Oncology
Volume 38, Issue 1 , Pages 107-110 , January 2002

Intracapsular carcinoma ex pleomorphic adenoma. Report of a case with unusual metastatic behaviour

  • A. Felix

      Affiliations

    • Departamento de Patologia Morfológica, Instituto Português de Oncologia de Francisco Gentil, Rua Professor Lima Basto, 1090-023 Lisboa, Portugal
    • Corresponding Author InformationCorresponding author. Tel.: +351-21-7200475; fax: +351-21-7228925
  • ,
  • J. Rosa-Santos

      Affiliations

    • Serviço de Cirurgia da Cabeça e do Pescoço, Instituto Português de Oncologia de Francisco Gentil, Rua Professor Lima Basto, 1090-023 Lisboa, Portugal
  • ,
  • M.E. Mendonça

      Affiliations

    • Departamento de Patologia Morfológica, Instituto Português de Oncologia de Francisco Gentil, Rua Professor Lima Basto, 1090-023 Lisboa, Portugal
  • ,
  • F. Torrinha

      Affiliations

    • Departamento de Imagiologia, Instituto Português de Oncologia de Francisco Gentil, Rua Professor Lima Basto, 1090-023 Lisboa, Portugal
  • ,
  • J. Soares

      Affiliations

    • Departamento de Patologia Morfológica, Instituto Português de Oncologia de Francisco Gentil, Rua Professor Lima Basto, 1090-023 Lisboa, Portugal

Received 4 January 2001 ,Accepted 29 January 2001.

References 

  1. Gnepp DR. Malignant mixed tumors of the salivary glands: a review. Pathol Annu. 1993;28:279–288
  2. Batsakis JG. Metastatic patterns of salivary gland neoplasms. Ann Otol Rhinol Laryngol. 1982;91:465–466
  3. Batsakis JG. Carcinoma ex pleomorphic adenoma's “big tent” has room for low- and high grade tumors. Adv Anat Pathol. 1997;4:176–178
  4. LiVolsi VA, Perzin KH. Malignant mixed tumors arising in salivary glands. I. Carcinomas arising in benign mixed tumors: a clinicopathological study. Cancer. 1977;39:2209–2230
  5. Tortoledo ME, Luna MA, Batsakis JG. Carcinoma ex pleomorphic adenoma and malignant mixed tumors: histomorphologic indexes. Arch Otolaryngol. 1984;110:172–176
  6. Brandwein M, Huvos AG, Dardick I, Thomas MJ, Theise ND. Non invasive and minimally invasive carcinoma ex mixed tumour. A clinicopathologic and ploidy study of 12 cases with major salivary tumors of low (or no?) malignant potential. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;81:655–664
  7. Costa Rosa J, Fonseca I, Félix A, Soares J. Immunohistochemical study of c-erbB-2 expression in carcinoma ex-pleomorphic adenoma. Histopathology. 1996;28:247–252
  8. Costa Rosa J, Fonseca I, Félix A, Soares J. p53 immunoexpression in carcinomas arising in pleomorphic adenoma. Int J Surg Pathol. 1996;3:257–262
  9. Félix A, Costa Rosa J, Fonseca I, Cidadao A, Soares J. Laminin and collagen IV in pleomorphic adenoma and carcinoma ex pleomorphic adenoma: an immunohistochemical study. Hum. Pathol. 1999;30:964–969
  10. In:  Seifert G,  Sobin LH editor. WHO International classification of tumours. Histological typing of salivary gland tumours, 2nd ed. Berlin Heidelberg: Spring-Verlag; 1991;
  11. Ellis GL, Auclair PL. Tumors of the salivary glands. Atlas of tumor pathology. 3rd ed. Washington, DC: Armed Forces Institute of Pathology; 1996;
  12. Batsakis JG, Bautina E. Metastases to major salivary glands. Ann Otol Rhinol Laryngol. 1990;99:501–503
  13. Greager JA, Wood D, Das Gupta TK. Metastatic cancer from undetermined primary site. J Surg Pathol. 1983;23:73–76

PII: S1368-8375(01)00023-9

Oral Oncology
Volume 38, Issue 1 , Pages 107-110 , January 2002