Oral Oncology
Volume 37, Issue 7 , Pages 586-592 , October 2001

Disturbances in craniofacial morphology in children treated for solid tumors

  • S. Karsila-Tenovuo

      Affiliations

    • Department of Oral Development and Orthodontics, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, FIN-20520 Turku, Finland
    • Corresponding Author InformationCorresponding author. Tel.: +358-2-333-8344; fax: +358-2-333-8256
  • ,
  • K. Jahnukainen

      Affiliations

    • Department of Pediatrics, University of Turku, PO Box 52, FIN-20521 Turku, Finland
  • ,
  • T. Peltomäki

      Affiliations

    • Department of Oral Development and Orthodontics, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, FIN-20520 Turku, Finland
  • ,
  • H. Minn

      Affiliations

    • Turku PET Center, University of Turku, PO Box 52, FIN-20521 Turku, Finland
    • Department of Oncology and Radiotherapy, University of Turku, PO Box 52, FIN-20521 Turku, Finland
  • ,
  • J. Kulmala

      Affiliations

    • Department of Oncology and Radiotherapy, University of Turku, PO Box 52, FIN-20521 Turku, Finland
  • ,
  • T.T. Salmi

      Affiliations

    • Department of Pediatrics, University of Turku, PO Box 52, FIN-20521 Turku, Finland
  • ,
  • O. Rönning

      Affiliations

    • Department of Oral Development and Orthodontics, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, FIN-20520 Turku, Finland

Received 24 November 2000 ,Accepted 6 December 2000.

References 

  1. Lombardi F, Navarria P, Gandola L. The evolving role of radiation therapy in the optimal multimodality treatment of childhood cancer. Tumori. 1998;84:270–273
  2. Eiser C. Practitioner review (long-term consequences of childhood cancer). Journal of Child Psychology and Psychiatry and Allied Disciplines. 1998;39:621–633
  3. Sklar C. Growth and neuroendocrine dysfunction following therapy for childhood cancer. Pediatric clinics of North Am. 1997;44:489–503
  4. Olshan JS, Gubernick J, Packer RJ, D'Angio GJ, Goldwein JW, Willi SM, et al.  The effects of adjuvant chemotherapy on growth in children with medulloblastoma. Cancer. 1992;70:2013–2017
  5. Chabner BA. Clinical stategies for cancer treatment (the role of drugs). In:  Chabner BA,  Collins JM editor. Cancer chemotherapy principles and practice. Philadelphia: JB Lippincott; 1990;p. 1–15
  6. Balis FM, Holcenberg JS, Poplack DG. General principles of chemoterapy. In:  Pizzo PA,  Poplack DG editor. Principles and practice of pediatric oncology. Philadelphia: Lippincott-Raven Publishers; 1997;p. 215–272
  7. Ilveskoski I, Saarinen UM, Wiklund T, Sipilä I, Mäkipernaa A, Perkkiö M, et al.  Growth impairment and growth hormone therapy in children treated for malignant brain tumors. European Journal of Pediatrics. 1997;156:764–769
  8. Leiper A. Growth hormone deficiency in children treated for leukemia. Acta Pediatrica Suppl. 1995;411:41–44
  9. Dahllöf G, Barr M, Bolme P, Modéer T, Lönnqvist B, Ringdén O, et al.  Disturbances in dental development after total body irradiation in bone marrow transplant recipients. Oral Surgery, Oral Medicine, Oral Pathology. 1988;65:41–44
  10. Sonis AL, Tarbell N, Valachovic RW, Gelber R, Schwenn M, Sallan S. Dentofacial development in long-term survivors of acute lymphoblastic leukemia (a comparison of three treatment modalities). Cancer. 1990;66:2645–2652
  11. Kaste SC, Hopkins KP, Jones D, Crom D, Greenwald CA, Santana VM. Dental abnormalities in children treated for acute lymphoplastic leukemia. Leukemia. 1997;11:792–796
  12. Näsman M, Forsberg C-M, Dahllöf G. Long-term dental development in children after treatment for malignant disease. European Journal of Orthodontics. 1997;19:151–159
  13. Dahllöf G, Forsberg C-M, Ringdén O, Bolme P, Borgström B, Näsman M, et al.  Facial growth and morphology in long-term survivors after bone marrow transplantation. European Journal of Orthodontics. 1989;11:332–340
  14. ICRU. Prescribing, Recording, and Reporting External Beam Radiation Treatments (Revision of ICRU Report 50). Washington, DC: ICRU News 1996;2: 16–8.
  15. Björk A. The face in profile. An anthropological X-ray investigation on Swedish children and conscripts. Svensk Tandläkare-Tidskrift 1947; 40 (Suppl. 5B).
  16. Rappaport R, Brauner R. Growth and endocrine disorders secondary to cranial irradiation. Pediatric Research. 1989;25:561–567
  17. Dahllöf G, Forsberg C-M, Näsman M, Mattsson T, Modeer T, Borgström B, et al.  Craniofacial growth in bone marrow transplant recipients treated with growth hormone after total body irradiation. Scandinavian Journal of Dental Research. 1991;99:44–47
  18. Simmons KE. Growth hormone and craniofacial changes (preliminary data from studies in Turner's syndrome). Pediatrics. 1999;104:1021–1024
  19. Kjellberg H, Beiring M, Albertsson Wikland K. Craniofacial morphology, dental occlusion, tooth eruption, and dental maturity in boys of short stature with or without growth hormone deficiency. European Journal of Oral Sciences. 2000;108:359–367
  20. Dahllöf G, Forsberg C-M, Borgström B. Changes in craniofacial develoment induced by growth hormone therapy in children treated with bone marrow transplantation. Acta Paediatrica. 1994;83:1165–1169
  21. Rongen-Westerlaken C, von der Born E, Prahl-Andersen B, von Teunenbroek A, Manesse P, Otten BJ, et al.  Effect of growth hormone treatment on craniofacial growth in Turner's syndrome. Acta Paediatrica. 1993;82:364–368
  22. Visnapuu V, Peltomäki T, Rönning O, Syrjänen S. Insulin-like Growth Factor (IGF-I) mRNA Distribution on Rat Mandibular Condyle and Growth Plate of Rib During Growth. Unpublished manuscript.
  23. Baume LJ. Principles of cephalofacial development revealed by experimental biology. American Journal of Orthodontics. 1961;47:881–901
  24. Glasser DB, Duane K, Lane JM, Healey JH, Caparros-Sison B. The effect of chemotherapy on growth in the skeletally immature individual. Clinical Orthopaedics and Related Reaserch. 1991;262:93–100
  25. Katz JA, Pollock BH, Jacaruso D, Morad A. Final attained height in patients successfully treated for childhood acute lymphoblastic leukemia. Journal of Paediatrics. 1993;123:546–552
  26. Sklar C, Mertens A, Walter A, Mitchell D, Nesbit M, O'Leary M, et al.  Final height after treatment for childhood acute lymphoblastic leukemia (comparison of no cranial irradiation with and 2400 centigrays of cranial irradiation). Journal of Paediatrics. 1993;1800:123;59-64
  27. Holtgrave EA, Heinze F, Henze G. Die Bedeutung einer präventiven ZNS-bestrahlung im rahmen einer antineoplastischen therapie im kindesalter hinsichtlich dentogener und mandibulofazialer spätschäden. Fortschritte Kieferortopedie. 1995;56:254–264
  28. Karsila S, Jahnukainen K, Salmi TT, Rönning O. Catch-up growth and craniofacial dimensions following administration of the antineoplastic agent vincristine to young rats. European Journal of Oral Sciences. 2000;108:426–431
  29. Wallace WH, Shalet SM. Chemotherapy with actinomycin D influences the growth of the spine following abdominal irradiation. Medical and Pediatric Oncology. 1992;20:177
  30. Gustafsson G, Langmark F, Pihkala U, de Verdier B, Lilleaas I. Childhood Cancer in the Nordic Countries (Report on epidemiologic and therapeutic results from registries and working groups). 1998:11–22 (NOPHO Annual meeting 1998, Reykjavik).
  31. Jannoun L. Are cognitive and educational development affected by age at which prophylactic therapy is given in acute lymphoblastic leukaemia?. Archives of Disease in Childhood. 1983;58:953–958
  32. Waber DP, Urion DK, Tarbell NJ, Niemeyer C, Gelber R, Sallan SE. Late effects of central nervous system treatment of acute lymphoblastic leukemia in childhood are sex-dependent. Developmental Medicine and Child Neurology. 1990;32:238–248
  33. Morrish RB, Chan E, Silverman S, Meyer J, Fu KK, Greenspan D. Osteonecrosis in patients irradiated for head and nech carsinoma. Cancer. 1981;47:1980–1983

PII: S1368-8375(01)00002-1

Oral Oncology
Volume 37, Issue 7 , Pages 586-592 , October 2001