Oral Oncology
Volume 37, Issue 1 , Pages 65-71 , January 2001

Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro

Received 3 May 2000 ,Accepted 17 May 2000.

References 

  1. Fidler IJ. Selection of successive tumour lines for metastasis. Nature. 1973;242:148–149
  2. Sato H, Takahina T, Okada Y, Cao J, Shinagawa A, Yamamoto E, et al.  A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature. 1994;370:61–65
  3. Brooks PC, Strömblad S, Sanders LC, Schalscha TL, Aimes RT, Stetler-Stevenson WG, et al.  Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αV β3. Cell. 1996;85:683–693
  4. Sato F, Shimada Y, Watanabe G, Uchida S, Makino T, Imamura M. Expression of vascular endothelial growth factor, matrix metalloproteinase-9 and E-cadherin in the process of lymph node metastasis. Br. J. Cancer. 1999;80:1366–1372
  5. Frixen UH, Behrens J, Sachs Eberle G, Voss B, Warda A, Löchner D, et al.  E-cadherin-mediated cell–cell adhesion prevents invasiveness of human carcinoma cells. J. Cell Biol. 1991;113:173–185
  6. Oka H, Shiozaki H, Kobayashi K, Inoue M, Tahara H, Kobayashi T, et al.  Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res. 1993;53:1696–1703
  7. Doki Y, Shiozaki H, Tahara H, Inoue M, Oka H, Iihara K, et al.  Correlation between E-cadherin expression and invasion in vitro in a human esophageal cancer cell line. Cancer Res. 1993;53:3421–3426
  8. Wilding J, Vousden KH, Soutter WP, McCrea PD, Buono RD, Pignatelli M. E-cadherin transfection down-regulates the epidermal growth factor receptor and reverse the invasive phenotype of human papilloma virus-transfected keratinocyte. Cancer Res. 1996;56:5285–5292
  9. Hoteiya T, Hayashi E, Satomura K, Kamata N, Nagayama M. Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo. J. Oral Pathol. Med. 1999;28:107–111
  10. Yoshiura K, Kanai Y, Ochiai A, Shinomiya Y, Sugimura T, Hirohashi S. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc. Natl. Acad. Sci. USA. 1995;92:7416–7419
  11. Ewing CM, Ru N, Morton RA, Robinson JC, Wheelock MJ, Johnson KR, et al.  Chromosome 5 suppresses tumorigenicity of PC3 prostate cancer cells: correlation with re-expression of α-catenin and restoration of E-cadherin function. Cancer Res. 1995;55:4813–4817
  12. Graff JR, Herman JG, Lapidus RG, Chopra H, Xu R, Jarrard DF, et al.  E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res. 1995;55:5195–5199
  13. Wakatsuki S, Watanabe R, Saito K, Saito T, Katagiri A, Sato S, et al.  vb. Loss of human E-cadherin (ECD) cprrelated with invasiveness of transitional cell in the renal pelvis, ureter and urinary bladder. Cancer Letter. 1996;103:11–17
  14. Ogawa K, Yamada Y, Kishibe K, Ishizaki L, Tokusashi Y. β-catenin mutation are frequent in hepatocellular carcinoma but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice. Cancer Res. 1999;59:1830–1833
  15. Miyaki M, Tanaka K, Kikuchi-Yanoshita R, Muraoka M, Konishi M, Takeichi M. Increased cell-substratum adhesion, and decreased gelatinase secretion and cell growth, induced by E-cadherin transfection of human colon carcinoma cells. Oncogene. 1995;11:2457–2552
  16. Llorens A, Rodrigo Lopez-Barcons L, Gonzalez-Garrigues M, Lozano E, Vinyals A, Quintanilla M, et al.  Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression. Lab. Invest. 1998;78:1131–1142
  17. Kuniyasu H, Ellis LM, Evans DB, Abbruzzese JL, Fenoglio CJ, Bucana CD, et al.  Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome patients with resectable pancreatic carcinoma. Clin. Cancer Res. 1999;5:25–33
  18. Tetsu O, McCormick F. β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999;398:422–426
  19. Luo J, Lubaroff DM, Hendrix MJC. Supression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection. Cancer Res. 1999;59:3552–3556
  20. Crawford HC, Fingleton BM, Rudolph-Owen LA, Goss KJH, Rubinfeld B, Polakis P, et al.  The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors. Oncogene. 1999;18:2883–2891
  21. Behrens J, Lowrick O, Klein-Hitpass L, Birchmeier W. The E-cadherin promoter (functional analysis of a GC-rich region and an epithelial cell-specific palindromic regulatory element). Proc. Natl. Acad. Sci. USA. 1991;88:11495–11499
  22. Bussenmakers MJG, Giroldi LA, Bokhoven A, Schalken JA. Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines. Biochem. Biophys. Res. Commun. 1994;203:1284–1290
  23. Henning G, Löwrick O, Birchmeire W, Behrens J. Mechanisms identified in the transcriptional control of epithelial gene expression. J. Biol. Chem. 1996;271:595–602
  24. Giroldi L, Bringuier P, Weijert M, Jansen C, Bokhoven A, Schalken JA. Role of E boxes in the repression of E-cadherin expression. Biochem. Biophys. Res. Commun. 1997;241:453–458
  25. Leptin M, Grunewald G. Cell shape changes during gastrulation in Drosophila. Development. 1990;110:73–84
  26. Smith DE, Amo FF, Gridley T. Isolation of Sna, a mouse gene homologous to Drosophila genes snail and escargot (its expression pattern suggests multiple roles during postimplantation development). Development. 1992;116:1033–1039
  27. Nieto MA, Bennett MF, Sargent MG, Wilkinson DG. Cloning and developmental expression of Sna, a murine homologue in the Drosophila snail gene. Development. 1992;116:227–237
  28. Hayashi S, Hirose S, Metcalfe T, Shirras AD. Control of imaginal cell development by the escargot gene of Drosophila. Development. 1993;118:105–115
  29. Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, Barrio MG, et al.  The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2000;2:76–83
  30. Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, et al.  The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2000;2:84–89
  31. Mattijssen V, Peters HM, Schalkwijk L, Manni JJ, Hof-Grootenboer BV, Mulder PHM, et al.  E-cadherin expression in head and neck squamous-cell carcinoma is associated with clinical outcome. Int. J. Cancer. 1993;55:580–585
  32. Shinohara M, Hiraki A, Ikebe T, Nakamura S, Kurahara S, Shirasuna K, et al.  Immnohistochemical study of desmosomes in oral squamous cell carcinoma: correlation with cytokeratin and E-cadheirn staining, and with tumour behaviour. J. Pathol. 1998;184:369–381
  33. Yamada K, Jordan R, Mori M, Speight PM. The relationship between E-cadherin expression, clinical stage and tumour differentiation in oral squamous cell carcinoma. Oral Disease. 1997;3:82–85
  34. Kamata N, Chida K, Rikimaru K, Horikoshi M, Enomoto S, Kuroki T. Growth-inhibitory effect of epidermal growth factor and overexpression of its receptor on human squamous cell carcinomas in culture. Cancer Res. 1986;46:1648–1653
  35. Hayashi E, Rikimaru K, Nagayama M. Simultaneous production of G- and M-CSF by an oral cancer cell line and the synergistic effects on associated leucocytosis. Oral Oncol. Eur. J. Cancer. 1995;31B:323–327
  36. Cunningham BA, Leutzinger Y, Gallin WJ, Sorkin BC, Edelman GM. Linear organization of the liver cell adhesion molecule L-CAM. Proc. Natl. Acad. Sci. USA. 1984;81:5787–5791
  37. Bell E, Ehrlich HP, Buttle DJ, Nakatsuji T. Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness. Science. 1981;211:1052–1054
  38. Tsunegawa M, Kohno Y, Yasumoto S, Huh N, Tachikawa T, Yoshiki S, et al.  Growth and differentiation properties of normal and transfomed human keratinocytes in organotypic culture. Jpn. J. Cancer Res. 1994;85:238–244
  39. Kamata N, Yokoyama K, Fujimoto R, Ueda N, Hayashi E, Nakanishi H, et al.  Growth of normal oral keratinocytes and squamous cell carcinoma cells in a novel protein-free defined medium. In Vitro Cell. Dev. Biol. Animal. 1999;35:635–641

PII: S1368-8375(00)00059-2

Oral Oncology
Volume 37, Issue 1 , Pages 65-71 , January 2001

Article Tools

* Image Usage & Resolution